You already know about my adventures in digital inking, if you've read these posts on my sketch blog: Inking in Flash, Inking in Illustrator (calligraphic brush), and Inking in Illustrator (art brushes).
Now I've been trying out Manga Studio. I have to say, I think it's pretty awesome! Here are some examples, with different settings on the brushes. With some more dabbling, I think I could figure out several more nice looking methods, too.
I definitely found it faster, easier, more fun, and more accurate to my intentions than inking in Flash or Illustrator.
I've been using the non-vector style, but it can also do vector inking, and I suspect it would be good for that, too. (But note: You only get the vector option if you pay for the expensive version of Manga Studio.)